Unruptured ampullary ectopic pregnancy at 13 weeks of gestation with positive cardiac activity: an exceptional entity
Salah Houda, Taamallah Meriem
Corresponding author: Salah Houda, Department of Gynecology and Obstetrics of Nabel, University of Tunis El Manar, Faculty of Medicine of Tunis, Tunis, Tunisia 
Received: 27 Jun 2026 - Accepted: 03 Jul 2026 - Published: 27 Jul 2026
Domain: Gynecology
Keywords: Pregnancy, extra uterin
Funding: This work received no specific grant from any funding agency in the public, commercial, or non-profit sectors.
©Salah Houda et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Salah Houda et al. Unruptured ampullary ectopic pregnancy at 13 weeks of gestation with positive cardiac activity: an exceptional entity. Pan African Medical Journal. 2026;54:100. [doi: 10.11604/pamj.2026.54.100.54230]
Available online at: https://www.panafrican-med-journal.com//content/article/54/100/full
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Unruptured ampullary ectopic pregnancy at 13 weeks of gestation with positive cardiac activity: an exceptional entity
Unruptured ampullary ectopic pregnancy at 13 weeks of gestation with positive cardiac activity: an exceptional entity
&Corresponding author
An ectopic pregnancy is a major gynecological emergency. Most ectopic pregnancies rupture early-typically between 6 and 10 weeks of gestation-especially when fetal cardiac activity is present. Discovering an unruptured ectopic pregnancy at an advanced gestational age of 13 weeks in a hemodynamically stable patient is an exceptionally rare clinical scenario. We report the case of a 20-year-old patient with no significant medical or surgical history who presented to the Gynecological Emergency Department with moderate, chronic pelvic pain and 13 weeks of amenorrhea. Upon admission, the patient was in excellent general condition and hemodynamically stable (blood pressure 120/70 mmHg, heart rate 80 bpm). Abdominal examination revealed mild tenderness in the left iliac fossa. Transabdominal and transvaginal pelvic ultrasound revealed an empty uterus and a large adnexal mass corresponding to an extra-uterine gestational sac. This sac contained a live fetus with clearly visible cardiac activity and a crown-rump length consistent with 13 weeks of gestation. The absence of free fluid in the pouch of Douglas confirmed that the ectopic pregnancy had not ruptured. The patient underwent emergency surgery via laparotomy. Intraoperative exploration confirmed a large, intact left tubal ectopic pregnancy with no hemoperitoneum. A salpingectomy was successfully performed. The immediate and long-term postoperative course was uneventful, and the patient was discharged on the first postoperative day. This clinical case highlights the importance of never ruling out an ectopic pregnancy at an advanced gestational age, even in a young, asymptomatic, and hemodynamically stable patient.
Figure 1: intraoperative image of an ectopic pregnancy at 13 weeks of gestation



