Barry Perkins young syndrome
Ashwin Karnan, Anjana Ledwani
Corresponding author: Image in medicine, Figure
Received: 10 Feb 2024 - Accepted: 22 Mar 2024 - Published: 16 Apr 2024
Domain: Infectious disease,Internal medicine,Pulmonology
Keywords: Cough, infertility, sinusitis, bronchiectasis
©Ashwin Karnan et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Ashwin Karnan et al. Barry Perkins young syndrome. Pan African Medical Journal. 2024;47:191. [doi: 10.11604/pamj.2024.47.191.42932]
Available online at: https://www.panafrican-med-journal.com/content/article/47/191/full
Barry perkins young syndrome
&Corresponding author
A 28-year-old male presented with complaints of fever, cough with expectoration and difficulty in breathing for the past 5 days. Patient is a fruit seller by occupation and gives history of similar illness in the past due to recurrent sinusitis and a significant treatment history for infertility for the past 2 years. Computed tomography of the chest showed tree in bud appearance predominantly in the upper lobes, with cystic and tractional bronchiectasis changes in the bilateral lower lobes. A transrectal ultrasound confirmed obstructive azoospermia for which he was advised vasoepididymostomy. A diagnosis of Young´s syndrome was made, and he was treated with intravenous antibiotics. Young´s syndrome also known as Barry perkins young syndrome or sinusitis-infertility syndrome is a rare, inherited syndrome commonly seen in middle-aged men with chronic rhinosinusitis, nasal polyps, infertility and bronchiectasis. It is named after Dr. Donald Young, a urologist who first described it. The exact cause is unknown, but childhood exposure to mercury and genetic factors are speculated. Treatment involves control of sinus, lung infection and surgical/assisted measures for reproduction.
Figure 1: computed tomography of the chest showing bilateral variable sized cystic and tractional bronchiectatic changes