Rubeosis iridis
Dionysios Pagoulatos, Constantine Georgakopoulos
The Pan African Medical Journal. ;28:279. doi:10.11604/pamj..28.279.13717

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Rubeosis iridis

Dionysios Pagoulatos, Constantine Georgakopoulos
Pan Afr Med J. 2017; 28:279. doi:10.11604/pamj.2017.28.279.13717. Published 29 Nov 2017

A 49 year-old man with medical history of diabetes type 2, who presented to the ophthalmology clinic for decreased vision. His most recent hemoglobin A1c was 11.4%. His intraocular pressures were 19 mmHg OD and 35 mmHg OS. Posterior segment exam showed severe proliferative diabetic retinopathy in both eyes. Neovascularization of the iris (NVI), also known as rubeosis iridis, is when, blood vessels develop on the anterior surface of the iris in response to retinal ischemia. This condition is often associated with diabetes in advanced proliferative diabetic retinopathy, central retinal vein occlusion, ocular ischemic syndrome and chronic retinal detachment. These new blood vessels may cover the trabecular meshwork and give rise to neovascular glaucoma. Patients with NVI are prone to spontaneous hyphemas as these blood vessels are fragile. Patients with proliferative diabetic retinopathy who develop NVI are treated with panretinal photocoagulation with or without an intravitreal injection of an anti-VEGF medication and with glaucoma treatment.

Corresponding author:
Dionysios Pagoulatos, Department of Ophthalmology, Hippokration Hospital, Athens, Greece

©Dionysios Pagoulatos et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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