Synovial cell sarcoma

Ahmed Nugud, Shomous Nugud

PAMJ. 2019; 33:291. Published 08 Aug 2019 | doi:10.11604/pamj.2019.33.291.18741

Thirty-nine years old patient presented to the emergency department with left-sided chest pain for four months and 4kg weight loss through the same period. Physical examination showed bulging of the left scapula which is tender to touch and decreased breath sounds on the left side. Chest X-ray done in ED showed opaque left hemithorax with rib resections. A CT was done showing a heterogeneous mass shadow with a solid and cystic component associated with linear calcifications causing a near total collapse of the left lung with shifting of the mediastinum to the right side. Similar findings were seen on an MRI. A PET-CT scan showed hypermetabolic complex mass occupying most of the left hemithorax infiltrating the back muscles bulging to the subcutaneous fat with Irregular thick active gastric mucosa as well and intense large colon activity. A biopsy of the lesion and immunohistochemical studies were done and showed malignant diffuse spindle cell neoplasm positive for CD56, CD99, Bcl2 CKAE1/AE3, H. Caldesmon and EMA. The patient was started on IFOS/DOX chemotherapy regimen and completed three cycles uneventfully.
Corresponding author
Ahmed Nugud, Aljalila ChildrenÂ’s Hospital, Dubai, United Arab Emirates (a7md13@gmail.com)

This image

Articles published in PAMJ are Open Access and distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0).

eISSN: 1937-8688


The Pan African Medical Journal (ISSN: 1937-8688) is a subsidiary of the Pan African Medical Journal. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.

Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, ESCI

Physical address: Kenya: 3rd Floor, Park Suite Building, Parkland Road, Nairobi. PoBox 38583-00100, tel: +254 (0)20-520-4356 | Cameroon: Immeuble TechnoPark Essos, Yaounde, PoBox: 10020 Yaounde, tel: +237 (0)24-309-5880