Images in clinical medicine | Volume 40, Article 134, 03 Nov 2021 | 10.11604/pamj.2021.40.134.32076

Nasal sarcoidosis

Fadwa Mekouar, Mohamed Elqatni

Corresponding author: Fadwa Mekouar, Internal Medicine B, Mohammed V Military Teaching Hospital, Sidi Mohamed Ben Abdellah University, Fes, Morocco

Received: 17 Oct 2021 - Accepted: 26 Oct 2021 - Published: 03 Nov 2021

Domain: Infectious disease,Internal medicine,Rheumatologist

Keywords: Sarcoidosis, granulomatous disease, diagnosis

©Fadwa Mekouar et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Fadwa Mekouar et al. Nasal sarcoidosis. Pan African Medical Journal. 2021;40:134. [doi: 10.11604/pamj.2021.40.134.32076]

Available online at: https://www.panafrican-med-journal.com/content/article/40/134/full

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Images in clinical medicine

Nasal sarcoidosis

Nasal sarcoidosis

Fadwa Mekouar1,&, Mohamed Elqatni1

 

1Internal Medicine B, Mohammed V Military Teaching Hospital, Sidi Mohamed Ben Abdellah University, Fes, Morocco

 

 

&Corresponding author
Fadwa Mekouar, Internal Medicine B, Mohammed V Military Teaching Hospital, Sidi Mohamed Ben Abdellah University, Fes, Morocco

 

 

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A 19-year-old woman with a two years history of dragging oto-rhino-laryngeal infections, purulent rhinorrhea and sinusitis, polyarthralgia, and an episode of granulomatous uveitis. Clinical examination showed destruction of nasal wing, hepatomegaly and splenomegaly. A rounded lesion with atrophic center in the forearm. Laboratory tests revealed upper limit calcemia, the angiotensin-converting enzyme was high 323 UI/L. Nasal biopsy revealed non-caseating epithelioid-cell granulomas. Differential diagnosis includes granulomatous disease of the nose such as leprosy, tuberculosis and Wegener´s granulomatosis. Special staining for typical mycobacterium and lepra bacilli were negative. The polymerase chain reaction for mycobacterium tuberculosis was negative. There was no renal involvement and the cytoplasmic antineutrophil cytoplasmic antibody (cANCA/PR3/ANCA) was negative. The diagnosis of nasal sarcoidosis was retained. The patient was treated with prednisone and azathioprine with favorable outcome.

 

 

Figure 1: A) destruction of nasal wing, B) rounded lesion with atrophic center in the forearm

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Images in clinical medicine

Nasal sarcoidosis

Images in clinical medicine

Nasal sarcoidosis

Images in clinical medicine

Nasal sarcoidosis

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Sarcoidosis

Granulomatous disease

Diagnosis

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