Images in clinical medicine | Volume 40, Article 130, 02 Nov 2021 | 10.11604/pamj.2021.40.130.31983

Chronic tophaceous gout

Husam Bader, Rama Maghnam

Corresponding author: Husam Bader, Monmouth Medical Center, Long Branch, New Jersey, United States of America

Received: 10 Oct 2021 - Accepted: 23 Oct 2021 - Published: 02 Nov 2021

Domain: Internal medicine,Rheumatologist,Rheumatology

Keywords: Chronic, tophaceous, gout

©Husam Bader et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Husam Bader et al. Chronic tophaceous gout. Pan African Medical Journal. 2021;40:130. [doi: 10.11604/pamj.2021.40.130.31983]

Available online at: https://www.panafrican-med-journal.com/content/article/40/130/full

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Images in clinical medicine

Chronic tophaceous gout

Chronic tophaceous gout

Husam Bader1,&, Rama Maghnam1

 

1Monmouth Medical Center, Long Branch, New Jersey, United States of America

 

 

&Corresponding author
Husam Bader, Monmouth Medical Center, Long Branch, New Jersey, United States of America

 

 

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Fifty-eight (58) year-old male with gouty arthritis for over 12 years, other medical history pertinent for hypertension, CKD stage 3 and heavy alcohol use. Patient described irregular usage of colchicine and urate-lowering drug for the last 10 years due to noncompliance with therapy. On physical examination, the patient was confined to a wheelchair because of his severe arthritis, he had deforming tophi and active synovitis of bilateral small joints of the hands (A), flexor tendon contractures (B), massive right big toe tophus (C) and concomitant septic arthritis and tophaceous gout of the left foot and ankle (D). Laboratory data were as follows: uric acid, 8.9 mg/dl; C-reactive protein (CRP): 33.5 mg/dl; creatinine, 2.8 mg/dl; blood and left ankle fluid cultures grew MRSA. Patient was treated emergently with IV antibiotics and subsequent below knee amputation as the foot was deemed clinically and radiographically unsalvageable. Patient was later started on febuxostat. After 4 months of therapy with febuxostat, he had no active synovitis. He was able to get out of the wheelchair and his CRP (0.4 mg/dl) and uric acid (4.2 mg/dl, the target is < 5 mg/dl) levels normalized. In addition, not only the tophaceous burden lessened but also the joint mobility improved, probably owing to control of the inflammation.

 

 

Figure 1: chronic tophaceous gout due to medication non-compliance; deforming tophi and active synovitis of bilateral small joints of the hands (A), flexor tendon contracture(B), massive right big toe tophus (C) and concomitant septic arthritis and tophaceous gout of the left foot and ankle (D)

 

 

 

 

 

 

 

 

 

 

 

 

Images in clinical medicine

Chronic tophaceous gout

Images in clinical medicine

Chronic tophaceous gout

Images in clinical medicine

Chronic tophaceous gout

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