Images in clinical medicine | Volume 39, Article 31, 11 May 2021 | 10.11604/pamj.2021.39.31.27959

Rare case of syphilis presenting with labial chancre

Surya Besant Natarajan, Krishna Prasanth Baalann

Corresponding author: Surya Besant Natarajan, Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, India

Received: 20 Jan 2021 - Accepted: 01 Feb 2021 - Published: 11 May 2021

Domain: Dermatology,Community health,Health Research

Keywords: Sexually transmitted diseases, chancre, syphilis

©Surya Besant Natarajan et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Surya Besant Natarajan et al. Rare case of syphilis presenting with labial chancre. Pan African Medical Journal. 2021;39:31. [doi: 10.11604/pamj.2021.39.31.27959]

Available online at: https://www.panafrican-med-journal.com/content/article/39/31/full

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Images in clinical medicine

Rare case of syphilis presenting with labial chancre

Rare case of syphilis presenting with labial chancre

Surya Besant Natarajan1,&, Krishna Prasanth Baalann2

 

1Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, India

 

 

&Corresponding author
Surya Besant Natarajan, Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research, Chennai, India

 

 

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Syphilis is a chronic inflammatory disease which is caused by the spirochete Treponema pallidum (T. pallidum) and is often sexually transmitted. The primary stage in syphilis classically presents with a painless ulcer which is evident in the genital area in more than 90% of patients and is commonly called as chancre. Extra genital chancres may differ from the classic ones based on the portal of entry of the organism, in terms of localization, size, depth, base and edges thus, they may cause diagnostic problems. A 27-year-old male presented with a 2-week history of a painless, ulcerative lesion on his lower lip. He gave a history of multiple sexual exposures and unprotected sex. On examination, he had a 2 x 2 cm nodular ulcer on his lower lip, palpable non-tender submental lymphadenopathy over the left side of the neck. Venereal Disease Research Laboratory (VDRL) test was reactive at 30 dilutions and T. pallidum hemagglutination (TPHA) test was positive. A fluorescent antibody test for T. pallidum showed positive for T. pallidum specific IgG and IgM. HIV testing was negative. Syphilis was confirmed, and findings were consistent with both primary (oral chancre and lymphadenopathy) and secondary (macular rash) disease. For treatment, the patient was given benzathine penicillin in 2.4 million units intramuscularly weekly once for three continuous weeks.

 

 

Figure 1: nodular ulcer on lower lip

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Images in clinical medicine

Rare case of syphilis presenting with labial chancre

Images in clinical medicine

Rare case of syphilis presenting with labial chancre

Images in clinical medicine

Rare case of syphilis presenting with labial chancre

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