Images in clinical medicine | Volume 39, Article 239, 13 Aug 2021 | 10.11604/pamj.2021.39.239.30886

Gorlin-Goltz syndrome without cutaneous manifestations

Rohan Kumar Singh, Gaurav Vedprakash Mishra

Corresponding author: Rohan Kumar Singh, Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, India

Received: 22 Jul 2021 - Accepted: 07 Aug 2021 - Published: 13 Aug 2021

Domain: Oral and Maxillofacial Radiology,Radiology,Maxillofacial surgery

Keywords: Computerized tomography (CT) scan, Gorlin-Goltz syndrome, odontogenic keratocyst, PTCH gene mutation

©Rohan Kumar Singh et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Rohan Kumar Singh et al. Gorlin-Goltz syndrome without cutaneous manifestations. Pan African Medical Journal. 2021;39:239. [doi: 10.11604/pamj.2021.39.239.30886]

Available online at: https://www.panafrican-med-journal.com/content/article/39/239/full

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Images in clinical medicine

Gorlin-Goltz syndrome without cutaneous manifestations

Gorlin-Goltz syndrome without cutaneous manifestations

Rohan Kumar Singh1,&, Gaurav Vedprakash Mishra2

 

1Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, India

 

 

&Corresponding author
Rohan Kumar Singh, Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, India

 

 

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A 29-year-old male visited the outpatient department of Acharya Vinoba Bhave Rural Hospital, Sawangi with chief complaints of swelling in the left lower jaw for 15 days. He had a past history of similar swelling on the right side of the jaw, for which he underwent intervention. The patient was referred from oral surgery to the Department of Radiodiagnosis for computed tomography scan of head and neck to know the extension of the lesion and underlying bony erosion. There was no significant family history or cutaneous manifestations. On computed tomography, there were multiple cystic lesions in the left hemimandible and maxilla. Histopathology revealed it to be Odontogenic keratocysts. Other findings included bilamellar falx cerebri and tentorium cerebelli calcifications, bridging sella, intracranial lipoma, spina bifida of C6 vertebra. The scalp was thickened with multiple foci of calcifications. Diagnosis of Gorlin-Goltz syndrome was made.

 

 

Figure 1: A) computed tomography image showing multiple cystic lesions in the left hemimandible and maxilla consistent with odontogenic keratocysts (red arrow); B) bilamellar falx cerebri and tentorium cerebelli calcifications (yellow arrow), bridging sella (blue arrow), intracranial lipoma (green arrow); C) spina bifida of C6 vertebra (white arrow); D) thickened scalp with multiple calcific foci (purple arrow); diagnosis of Gorlin-Goltz syndrome was made

 

 

 

 

Images in clinical medicine

Gorlin-Goltz syndrome without cutaneous manifestations

Images in clinical medicine

Gorlin-Goltz syndrome without cutaneous manifestations

Images in clinical medicine

Gorlin-Goltz syndrome without cutaneous manifestations