Original article | Volume 34, Article 141, 12 Nov 2019 | 10.11604/pamj.2019.34.141.18149

Congenital clitoromegaly in an adult

Mohammed Alae Touzani, Imad Ziouziou

Corresponding author: Mohammed Alae Touzani, Department of Urology « B », Avicenne Hospital, Rabat, Morocco

Received: 12 Jan 2019 - Accepted: 11 Nov 2019 - Published: 12 Nov 2019

Domain: Urology

Keywords: Clitoris, clitoromegaly, 21 hydroxylase, pseudo-hermaphroditism

©Mohammed Alae Touzani et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Mohammed Alae Touzani et al. Congenital clitoromegaly in an adult. Pan African Medical Journal. 2019;34:141. [doi: 10.11604/pamj.2019.34.141.18149]

Available online at: https://www.panafrican-med-journal.com/content/article/34/141/full

Home | Volume 34 | Article number 141

Original article

Congenital clitoromegaly in an adult

Congenital clitoromegaly in an adult

Mohammed Alae Touzani1,&, Imad Ziouziou2

 

1Department of Urology « B », Avicenne Hospital, Rabat, Morocco, 2Department of Urology, Hassan II Hospital, Ibn Zohr University, Agadir, Morocco

 

 

&Corresponding author
Mohammed Alae Touzani, Department of Urology « B », Avicenne Hospital, Rabat, Morocco

 

 

Image in medicine    Down

Clitoromegaly is an abnormal enlargement of the clitoris. In adult, dimensional criteria are, according to Brodie, a minimum length hood and width of 27.4mm and 8mm. We here report the case of a 26 year female patient, with no previous personal history, who consults for primary amenorrhea with androgenization signs (hirsutism, deep voice…). Clinical examination showed a clitoromegaly and urogenital sinus persistency. The patient first underwent a karyotype that shows a female karyotype with no abnormalities (46,XX). Further explorations showed a 21-hydroxylase deficiency, with a congenital bilateral adrenal hyperplasia. Congenital adrenal hyperplasia (CAH) is defined by an increased size and metabolism of the adrenal glands due to enzymatic disorders, such as 21-hydroxylase deficiency. In women, this can lead to virilization of the external genitalia in 11% of patients, and a late diagnosis, such in this case, may result in the late discovery of androgenization signs, such as clitoromegaly. The treatment is clitoroplasty, which consist to reduce the clitoris size and preserve its sensitivity, with a vaginoplasty if there is an association with urogenital sinus persistency, if the patient is asking for it.

 

Figure 1: clitoromegaly with a "male glans" aspect

 

 

 

 

 

 

 

 

 

 

 

 

Original article

Congenital clitoromegaly in an adult

Original article

Congenital clitoromegaly in an adult

Original article

Congenital clitoromegaly in an adult

Volume 36 (May - Aug 2020)
This article authors
On Pubmed
On Google Scholar
Citation [Download]
EndNote
Reference Manager
Zotero
BibTex
ProCite

Navigate this article
Key words

Clitoris

Clitoromegaly

21 hydroxylase

Pseudo-hermaphroditism

PlumX Metrics
Congenital clitoromegaly in an adult