Original article | Volume 34, Article 108, 23 Oct 2019 | 10.11604/pamj.2019.34.108.17999

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Salma Salim, Badreddine Hassam

Corresponding author: Salma Salim, Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco

Received: 21 Dec 2018 - Accepted: 16 Feb 2019 - Published: 23 Oct 2019

Domain: Dermatology,Infectious disease,Oncology

Keywords: Buschke-L÷wenstein tumor, human papilloma virus, immunocompetent patient

©Salma Salim et al. Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Salma Salim et al. Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient. Pan African Medical Journal. 2019;34:108. [doi: 10.11604/pamj.2019.34.108.17999]

Available online at: https://www.panafrican-med-journal.com/content/article/34/108/full

Home | Volume 34 | Article number 108

Original article

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Salma Salim1,&, Badreddine Hassam1

 

1Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco

 

 

&Corresponding author
Salma Salim, Dermatology and Venereology Department, Ibn Sina University Hospital, Rabat, Morocco

 

 

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We report the case of a 56-year-old man who presented with locally advanced giant condyloma acuminatum (Buschke-L÷wenstein tumor) after approximately 15 years of neglect due to hospital phobia. Clinical examination showed an extensive, erosive, exophytic and cauliflower-like growth involving his suprapubic, external genitalia and perianal region. No inguinal or supraclavicular lymphadenopathy was detected clinically. Histological study revealed a papillomatous and acanthotic epithelium with ortho and parakeratosis and koilocyte cells suggestive of HPV infection. No signs of malignant transformation were noted. Radiological investigations consisted of a thoracic-abdominal-pelvic computed tomography scan which showed the localization of this tumor in the external genitalia, perineal and suprapubic region without any lymph nodes or distant metastases. The results of biochemical and serological investigations including HIV test were normal. After discussion among the oncologist, radiotherapist, pathologist and surgeon, the patient initially received chemoradiotherapy, followed by extensive local excision with average outcome. Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It is a neoplasm of the anogenital region which has benign appearance on histopathology. It often grows over years in immunocompetent patients and can be highly destructive to local tissue. It carries a high recurrence rate and a significant potential for malignant transformation. Human papilloma virus (types 6 and 11) has been implicated as an etiologic agent for this tumor. Since this disease is rare and no controlled studies exist, radical excision of this anogenital lesion is generally recommended as the first line therapy and close vigilance and followup are essential.

 

 

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Figure 1: Buschke-Lowenstein tumor presenting as an extensive, erosive, exophytic and cauliflower-like growth involving the suprapubic, external genitalia and perianal region

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Original article

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Original article

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient

Original article

Extended anogenital Buschke-L÷wenstein tumor in an immunocompetent patient