Pseudotumoral form of granulomatosis with polyangiitis

Fadwa Mekouar, Naoual El Omri

PAMJ. 2017; 26:173. Published 27 Mar 2017 | doi:10.11604/pamj.2017.26.173.12195

A 65-year-old woman, non-smoker presented with a two-month history of cough. She also complained of arthralgia and weight loss. The clinical examination revealed a febrile patient. The chest radiograph and the scanner revealed right upper lobar mass, with spiculated contours (A, B). Biology showed an inflammatory syndrome. Polymerase chain reaction for Mycobacterium tuberculosis and tumor markers was negative. A lung biopsy showed non caseous granulomatous vasculitis. The cytoplasmic antineutrophil cytoplasmic antibody (cANCA/PR3/ANCA) showed a positive result; Wegener's granulomatosis was finally confirmed. The patient was treated with prednisone and cyclophosphamide with favorable outcome. A follow-up chest radiography two weeks after treatment showed resolving pulmonary lesions (C).
Corresponding author
Naoual El Omri, Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco (elomrinaoual@gmail.com)


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