Looking in the mirror: situs inversus totalis

Anastasia Paschala, Theocharis Koufakis

PAMJ. 2015; 20:87. Published 29 Jan 2015 | doi:10.11604/pamj.2015.20.87.6139

A 50 year-old male presented to the Emergency Department with complaints of abdominal pain. His chest and abdomen X-rays demonstrated some unexpected findings: dextrocardia (A) and right-sided stomach bubble (B). Further evaluation of the patient revealed a urinary tract infection as the cause of his symptoms. Situs inversus totalis is defined as the complete inversion of the thoracic and abdominal organs, which constitute a mirror image of the normal anatomy. It was first described by Matthew Baillie in the 16th century and is a rare, congenital condition, with an overall frequency estimated to be approximately at 1/10000 live births. The syndrome has a genetic background, following an autosomal recessive pattern of inheritance. Subjects with the condition are usually asymptomatic, as the structure and function of vital organs aregenerally unaffected. However, in 25% of the cases, the syndrome coexists with primary ciliary dyskinesia (Kartagener syndrome), then characterized by chronic sinusitis, bronchiectasis and susceptibility to infections. A random X-ray test for an unrelated condition is often the occasion that leads to the diagnosis. The clinical significance of situs inversus totalis relates to the fact that, due to the reversal of the inner organs, symptoms and signs elicited during patient's physical examination are present on the atypical side of the body.
Corresponding author
Theocharis Koufakis, Department of Internal Medicine, General Hospital of Larissa, Larissa, Greece (thkoyfak@hotmail.com)


The Pan African Medical Journal (ISSN: 1937-8688) is a subsidiary of the Pan African Medical Journal. The contents of this journal is intended exclusively for professionals in the medical, paramedical and public health and other health sectors.

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