Prenatal intraventricular hemorrhage in a term infant with congenital CMV infection
Imene Dahmane Ayadi, Emira Ben Hamida
The Pan African Medical Journal. 2015;22:244. doi:10.11604/pamj.2015.22.244.8156

Create an account  |  Sign in
PAMJ Conf Proceedings PAMJ Conf Proceedings
"Better health through knowledge sharing and information dissemination "

Images in medicine

Prenatal intraventricular hemorrhage in a term infant with congenital CMV infection

Cite this: The Pan African Medical Journal. 2015;22:244. doi:10.11604/pamj.2015.22.244.8156

Received: 14/10/2015 - Accepted: 31/10/2015 - Published: 13/11/2015

Key words: Congenital, cytomegalovirus, intraventricular hemorrhage, newborn

© Imene Dahmane Ayadi et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/22/244/full

Corresponding author: Imene Dahmane Ayadi, Department of Neonatology, Charles Nicole Hospital, Tunis El Manar University, Tunis, Tunisia (imen_ayadi@hotmail.com)


Prenatal intraventricular hemorrhage in a term infant with congenital CMV infection

 

Imene Dahmane Ayadi1,&, Emira Ben Hamida1

 

1Department of Neonatology, Charles Nicole Hospital, Tunis El Manar University, Tunis, Tunisia

 

 

&Corresponding author
Imene Dahmane Ayadi, Department of Neonatology, Charles Nicole Hospital, Tunis El Manar University, Tunis, Tunisia

 

 

Image in medicine

Intraventricular hemorrhage (IVH) occurs rarely in term infant, since subependymal area is a transient structure in fetal life. IVH in term infant indicates generally that it happened prenatally. Congenital cytomegalovirus (CMV) infection is frequent, occurring in 1% of live births. It is a severe infection leading to developmental defects, especially sensorineural deafness. The diagnosis of congenital CMV infection is rarely evoked in term eutrophic newborn. We report a term male neonate born to a 32-year-old mother gravida 2, para 2. Pregnancy was uneventful. Ultrasound follow-up was unmarked. The newborn was eutrophic, birth weight was 3400g, length was 49cm, and head circumference 33cm. Neonatal examination showed no anomalies. On the first day of life, blood cells count performed for suspected materno-fetal infection discovered fortuitous thrombocytopenia at 30 x 109/L. Within the second day of life, platelet level dropped to 20 x 109/L. Management of thrombocytopenia included multiple platelet transfusion. Cranial ultrasound on day one of life showed bilateral subependymal hemorrhage with cysts (A) and hydrocephaly (B), signs of prenatal occurrence. Platelet phenotypage rules out the diagnosis of allo-immune thrombocytopenia. Laboratory testing for rubella was negative. Blood PCR CMV was positive. Liver function tests noted the absence of hepatic cytolysis and cholestasis. The newborn received intravenous Ganciclovir® therapy. Hearing screening before discharge was negative. Bilateral deafness was diagnosed at 3 months of life.

 

 

Figure 1: (A) bilateral subependymal hemorrhage; (B) hydrocephaly

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


The Pan African Medical Journal articles are archived on Pubmed Central. Access PAMJ archives on PMC here

Volume 27 (May - August 2017)

Article tools

This article authors

On Pubmed
On Google Scholar

Navigate this article

Rate this article

Altmetric

Popular articles in Images in medicine

PAMJ is a member of the Committee on Publication Ethics

PAMJ is published in collaboration with the African Field Epidemiology Network (AFENET)
Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, Ulrichsweb, More to come . Member of COPE.

ISSN: 1937-8688. © 2017 - Pan African Medical Journal. All rights reserved