Bone lesion in Adult T Cell Lymphoma Leukemia
Zahra Mozaheb
The Pan African Medical Journal. 2013;16:76. doi:10.11604/pamj.2013.16.76.2706

Create an account  |  Sign in
Case studies in Public health Supplement 2 Supplement
"Better health through knowledge sharing and information dissemination "

Images in medicine

Bone lesion in Adult T Cell Lymphoma Leukemia

Cite this: The Pan African Medical Journal. 2013;16:76. doi:10.11604/pamj.2013.16.76.2706

Received: 08/04/2013 - Accepted: 04/11/2013 - Published: 04/11/2013

Key words: Bone lesion, Adult T Cell Lymphoma Leukemia, lytic bone lesion, HTLV1, Iran

© Zahra Mozaheb et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Available online at: http://www.panafrican-med-journal.com/content/article/16/76/full

Corresponding author: Zahra Mozaheb, Hematology-Oncology Department, Imam-Reza Hospital, Mashhad University of Medical Science, Mashhad, Iran (mozahebz@muma.ac.ir)


Bone lesion in Adult T Cell Lymphoma Leukemia

 

Zahra Mozaheb1,&

 

1Hematology-Oncology Department, Imam-Reza Hospital, Mashhad University of Medical Science, Mashhad, Iran

 

 

&Corresponding author
Zahra Mozaheb, Hematology-Oncology Department, Imam-Reza Hospital, Mashhad University of Medical Science, Mashhad, Iran

 

 

Image in medicine

A 57-year-old man from Khorasan Razavi presented with severe hypercalsemia and fever, with tempreture up to 40°C, over a 2-week period. He also had severe headache and generalized bone pain. He was admitted and treated for hypercalcemia. After two days hypercalcemia and fever were controlled and bone pain decreased mildly but his headache continued severely. At first day of admission he was not anemic but one week later he became anemic and thrombocytopenic with atytipical lymphocyte in peripheral blood smear. During patient assessment we found, hyperuricemia, elevated ESR,CRP and LDH. Skeletal radiographies showed severe lytic bone lesion, and brain CT scan was normal. Based on these data, bone marrow exam was done and serum anti HTLV1 was requested. After 3 days we noticed several depressions on the scalp and forehead of the patient because of severe bone resorption. Bone marrow exam showed a patchy lymphocyte infiltration, and serum anti HTLV1 antibody was positive. CD4 also was positive in flowcytomery. All this findings were compatible with Adult T cell Lymphoma Leukemia secondary to HTLV1 infection which is endemic in Khorasan Razavi, Iran. The patient was died before beginning of induction therapy.

Figure 1: Bone lesion in adult T cell lymphoma leukemia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


The Pan African Medical Journal articles are archived on Pubmed Central. Access PAMJ archives on PMC here

Volume 28 (September - December 2017)

Article tools

This article authors

On Pubmed
On Google Scholar

Navigate this article

Rate this article

Altmetric

PAMJ is a member of the Committee on Publication Ethics
Next abstract

PAMJ is published in collaboration with the African Field Epidemiology Network (AFENET)
Currently tracked by: DOAJ, AIM, Google Scholar, AJOL, EBSCO, Scopus, Embase, IC, HINARI, Global Health, PubMed Central, PubMed/Medline, Ulrichsweb, More to come . Member of COPE.

ISSN: 1937-8688. © 2017 - Pan African Medical Journal. All rights reserved