Table 1:  characteristics of patients with macrocytosis, acute leukemia and bone marrow failure

Patient

 

Diagnosis

Age

Gender

Wbc

/mm3

Neut

/mm3

Hgb

gr/dl

MCV

Plt

/mm3

Physical examination

LFT

TFT

B12-folat

1

AML M0

8

Male

41.990

8100

7,1

99

24.000

HSM

N

-

N

2

AML M6-DS

2

Female

12.980

1200

5,6

93

50.000

HSM

N

N

N

3

ALL

11

Female

44.780

440

5,4

94

14.000

HSM-LAP

N

-

N

4

ALL

4

Male

8270

180

7,5

89

24.000

HSM-LAP

N

N

N

5

ALL

15

Male

12.290

290

3,7

94

6000

HSM-LAP

N

N

N

6

ALL

8

Female

7670

1160

7,3

93

263.000

HSM-LAP

N

N

N

7

ALL

4

Male

7470

210

7,2

101

171.000

HSM-LAP

N

-

-

8

ALL

6

Female

12.690

260

7,3

90

26.000

HSM-LAP

N

-

-

9

ALL

10

Male

3920

270

6,6

94

67.000

HSM

N

N

-

10

ALL

3

Female

3320

600

11,4

89

193.000

HSM

2 fold increase

N

N

11

ALL

7

Male

39.630

540

6,6

94

34.000

HSM-LAP

N

-

N

12

ALL

12

Female

57.980

1370

3,4

107

67.000

HSM-LAP

N

N

N

13

ALL-DS

6

Female

26.850

880

5,5

102

25.000

HSM-LAP

N

N

N

14

FAA

11

Female

1860

220

8,5

98

38.000

GR, Cafe-au-lait spots

N

N

N

15

FAA

5

Male

3810

330

8,2

94

26.000

GR, Cafe-au-lait spots

N

N

N

16

FAA

4

Male

5710

1180

12

96

144.000

GR

N

N

N

17

FAA

5

Male

4020

2030

12,2

93

74.000

GR, Cafe-au-lait spots

N

N

N

18

FAA

5 Month

Male

9820

3560

5,4

101

323.000

microcephaly

N

N

N

19

FAA

6

Female

4320

1840

11,7

96

26.000

GR, Cafe-au-lait spots

N

N

N

20

FAA

2

Female

3330

1340

10,2

90

65.000

GR, Cafe-au-lait spots

N

N

N

21

AA

14

Female

2190

470

8,2

100

32.000

-

N

N

N

22

DBA

2

Male

5260

1520

7,5

103

462.000

GR

N

N

N

23

DBA

1,5

Female

9920

2820

6

89

446.000

-

N

N

N

24

CDA

13

Female

4740

3470

2,5

104

240.000

-

N

N

B12: 146

25

MFS-AML M7-DS

11 Month

Male

3170

890

5

94

17.000

HSM

N

N

Treated for hypothyroidism

N

Wbc: White blood cell count, neut: neutrophil count, hgb: hemoglobin, plt: thrombocyte count, MCV: Mean corpusculer volume, LFT: liver function tests, TFT:Thyroid function tests, AML: acute myeloid leukemia, ALL: acute lymphoid leukemia, FAA: Fanconi aplastic anemia, AA: aplastic anemia, DBA: Diamond–Blackfan anemia, CDA: congenital dysery thropoetic anemia, MFS: myelofibrozis, DS: Down syndrome, HSM: hepatosplenomegaly, LAP: lymphadenopathy, GR: Growth retardation