|
Table 4: severe paracetamol overdose: treatment and outcome |
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|
Authors |
Koivusalo et al [9] |
Sule et al [10] |
Our patient |
|
No. of patients |
5 |
1 |
1 |
|
Maximum number of paracetamol tablets ingested in g (per kg body weight) |
45g (473 mg/kg) |
60g (1200 mg/kg) |
50g (834mg/kg) |
|
Paracetamol blood levels (maximum) |
261.5mg/L at 24h |
207 mg/L At 6h |
900mg/L At 18h |
|
Initiation of NAC treatment |
After 18 hours |
Within 6 hours |
Within 6 hours |
|
Duration of NAC treatment |
24h |
72h |
72h (oral NAC) |
|
Liver failure |
Yes |
No |
No |
|
Outcome |
Death |
Survival |
Survival |
|
No. of days in hospital |
12 days |
5 days |
5 days |