Table 4: severe paracetamol overdose: treatment and outcome

Authors

Koivusalo et al [9]

Sule et al [10]

Our patient

No. of patients

5

1

1

Maximum number of paracetamol tablets ingested in g (per kg body weight)

45g

(473 mg/kg)

60g

(1200 mg/kg)

50g

(834mg/kg)

Paracetamol blood levels (maximum)

261.5mg/L

at 24h

207 mg/L

At 6h

900mg/L

At 18h

Initiation of NAC treatment

After 18 hours

Within 6 hours

Within 6 hours

Duration of NAC treatment

24h

72h

72h

(oral NAC)

Liver failure

Yes

No

No

Outcome

Death

Survival

Survival

No. of days in hospital

12 days

5 days

5 days