Table 2: paracetamol dosing that may be associated with hepatic injury
	Adults and children >6 years of age	Children aged 0-6 years
Acute single Ingestion	> 200mg/kg or 10 g (whichever is less) over a period of less than 8 hours	≥200mg/kg over a period of less than 8 hours
Repeated supratherapeutic ingestion	> 200mg/kg or 10 g (whichever is less) over a single 24-hour period > 150mg/kg or 6 g (whichever is less) per 24-hour period for the preceding 48 hours > 100mg/kg or 4 g/day (whichever is less) in patients with predisposing risk factors†	≥200mg/kg over a single 24-hour period ≥150mg/kg per 24-hour period for the preceding 48 hours ≥100mg/kg per 24-hour period for the preceding 72 hours
*Adapted from Dart et al. [2] † Such as chronic ethanol misuse, use of enzyme-inducing drugs, prolonged fasting, dehydration