Table 5: comparison of the means, standard deviations, medians and reference intervals of the blood count parameters for pregnant women studied according to the trimesters of pregnancy

Trimester

First trimester (n=1584)

Second trimester (n=1298)

Third trimester (n=927)

 

 

P value

Hematological parameters

Reference interval

Reference interval

Reference interval

Mean

SD

Median

Percentile  2.5

Percentile 97.5

Mean

SD

Median

Percentile 2.5

Percentile 97.5

Mean

SD

Median

Percentile 2.5

Percentile 97.5

RBCx1012/L

4.21

0.36

4.23

3.49

4.91

4.02

0.39

4.02

3.26

4.82

3.92

0.41

3.93

3.19

4.78

<0.001

HGB (g/dL)

12.23

0.93

12.3

10

13.9

11.68

0.96

11.7

9.6

13.6

11.22

1.06

11.3

9.1

13.4

<0.01

HCT (%)

35.87

2.83

36.2

29.8

40.9

34.44

2.94

34.5

28.6

39.9

33.20

2.98

33.1

27.34

39.3

<0.001

MCV (fL)

85.21

5.02

85.6

74.4

94.9

85.73

5.58

85.7

74.7

97.7

84.77

5.79

85

72.8

96.1

<0.001

MCH (pg)

29.14

2.19

29.3

24.2

32.9

29.17

2.36

29.4

24.0

33.3

28.71

2.56

28.9

23

33.4

<0.001

MCHC (g/dL)

34.13

1.43

34.2

31.3

36.6

34.01

1.47

34.1

31.2

36.6

33.82

1.45

34

30.8

36.2

<0.001

WBCx109 /L

7.52

1.78

7.5

4.5

11.6

8.03

2.02

7.9

4,6

12.6

9.53

2.39

9.5

5.3

14.3

<0.001

LYMx109/L

2.16

0.56

2.1

1.2

3.4

2.15

0.60

2.1

1.2

3.6

2.20

0.66

2.1

1.1

3.8

<0.001

MONx109 /L

0.49

0.28

0.4

0.1

1

0.53

0.28

0.5

0.2

1

0.62

0.29

0.6

0.1

1

<0.001

NEUx109/L

4.68

1.59

4.5

2.1

8.2

5.18

1.80

5.1

2.2

9.2

6.56

2.15

6.5

3

11

<0.001

EOSx109/L

0.16

0.15

0.1

0

0.4

0.14

0.14

0.1

0

0.4

0.09

0.13

0

0

0.4

<0.001

BASx109/L

0.01

0.03

0

0

0.09

0.02

0.04

0

0

0.1

0.02

0.04

0

0

0.1

<0.001

PLTx109/L

235.85

57.61

229

145

374

229.90

58.44

224

140

364

240.25

67.02

231

139

398

<0.001

MPV (fL)

10.97

1.20

10.8

8.9

13.7

10.98

1.23

10.9

8.9

13.5

10.64

1.20

10.6

8.9

13.2

<0.001

SD, standard deviation; RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; WBC, white blood cell; LYM, lymphocytes; MON, monocytes; NEU, neutrophils; EOS, eosinophils; BAS, basophils; PLT, platelets; MPV, mean platelet volume.

Mann-Whitney U-test for nonnormally distributed parameters was done between trimesters: All hematological parameters showed significant differences between first, second, and third trimester.

 P < 0.05 was considered as statistically significant.

Comparison between trimesters of pregnancy: Comparing the three groups two by two using a post-hoc test shows that there is a statistically significant difference between the three groups taken two by two