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Ugwu Anthony Chukwuka, Agwu Kenneth Kalu, Erondu Okechukwu Felix. Variabilities of gallbladder contraction indices and a simple regression model for gallbladder and gastric emptying ratio. The Pan African Medical Journal. 2011;9:11 Key words: Gallbladder, contraction indices, gastric empty ratio, variabilities Permanent link: http://www.panafrican-med-journal.com/content/article/9/11/full Received: 10/02/2011 - Accepted: 31/05/2011 - Published: 31/05/2011 © Ugwu Anthony Chukwuka et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Variabilities of gallbladder contraction indices and a simple regression model for gallbladder and gastric emptying ratio
Ugwu Anthony Chukwuka1, Agwu Kenneth Kalu2, Erondu Okechukwu Felix3,&
1Department of Radiography and Radiological sciences Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria, 2Department of medical radiography and Radiological sciences, University of Nigeria , Enugu campus, Enugu state, Nigeria, 3Department of clinical imaging, Image Diagnostics, Port Harcourt, Rivers State Nigeria
&Corresponding author
Erondu Okechukwu Felix, Department of clinical imaging, Image Diagnostics, Port Harcourt, Rivers State, Nigeria
The objective of this study was to assess the variabilities of gallbladder contraction indices (GBCI) and derive a predictive model for gallbladder and gastric motility.
The gallbladder volume and gastric antral measurements were obtained from 24 healthy male volunteers in preprandial and post-milk ingestion states. After preprandial measurement of the gallbladder volume and gastric antral area, each subject ingested 157 ml of full cream milk and 30 cl of ion -free water. In supine position, the gallbladder volume and the gastric antral area were obtained every five minutes for 40 minutes. For the gallbladder while only the 5 th, 10 th and 15 th measurement of gastric antral area were obtained. Gallbladder contraction indices were calculated and gastric emptying ratio obtained at the fifteenth minute is the indication of gastric motility. Statistical analyses were conducted using SPSS version 16.0 with p < 0.05 as criterion of statistical significance.
The GBCIs followed Gaussian response at some stages and did not at some other stages. The least variability occurred at the 35th measurement of GBCI. A cut- off value for the 35th minute GBCI value was established with the mean ± 2 SD (80.79 ± 11.5 %). Obvious gallbladder refilling was noted after 35minutes. A positive relationship was noted between gallbladder and gastric motilities.
With milk dilution, the variability of gall bladder motility is least at the 35th minute. A significant positive relationship between gastric emptying and gallbladder contraction index was also observed.
