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Zouhour Fadoukhair, Issam Lalya, Mounia Amzerin, Basma Elkhanoussi, Yassir Sbitti, Saber Boutayeb, Hind M’rabti, Noureddine Benjaafar, Hassan Errihani. Successful management of primary non Hodgkin’s lymphoma of the cranial vault. The Pan African Medical Journal. 2011;8:50 Key words: B-Cell lymphoma, primary bone lymphoma, extranodal lymphoma, cranial vault Permanent link: http://www.panafrican-med-journal.com/content/article/8/50/full Received: 25/03/2011 - Accepted: 24/04/2011 - Published: 30/04/2011 © Zouhour Fadoukhair et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Successful management of primary non Hodgkin’s lymphoma of the cranial vault
Zouhour Fadoukhair1, Issam Lalya2,&, Mounia Amzerin1, Basma Elkhanoussi3, Yassir Sbitti4, Saber Boutayeb1, Hind M’rabti1, Noureddine Benjaafar2, Hassan Errihani1
1Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco, 2Department of Radiation oncology, National Institute of Oncology, Rabat, Morocco, 3Department of pathology, National Institute of Oncology, Rabat, Morocco, 4Department of Medical Oncology, Military Instruction Hospital Mohammed V, Rabat, Morocco
&Corresponding author
Issam Lalya, Department of radiation oncology, National Institute of Oncology, Rabat, Morocco
Primary bone lymphoma (PBL) is a relatively uncommon entity. However, involvement of the cranial vault is an unusual manifestation of aggressive non-Hodgkin’s lymphoma. We report the case of a 42-year old immunocompetent woman who presented with an enlarging mass involving the right parietal bone. Magnetic resonance imaging (MRI) of the brain revealed an expansive tumor that affects the right parietal bone. Computed tomographic (CT) scans of the abdomen, chest and pelvis were negative for lymphadenopathy or organomegaly. Biopsy of the mass showed diffuse large B-cell non-Hodgkin’s lymphoma confirmed by immunohistochemical study. The patient had a complete response after 4 cycles of chemotherapy followed by external beam radiotherapy. After a follow-up of more than 9 months the patient is still in good local control without distant metastasis. The aim of our work is to report a case of Primary bone lymphoma of the cranial vault with good response to treatment combining sequential chemotherapy and radiotherapy.
