Home | Feedback | Contact us | Support the Journal | Sign in     01-Sep-2014
  • Key
  • Log in to email corresponding author
Log in to email corresponding author
  • Articles by author(s)

In Google Scholar

In PubMed

DHTML is the embodiment of a combination of technologies- JavaScript, CSS, and HTML. Through them a new level of interactivity is possible for the end user experience.

  • Social Bookmark ?
  • Del.icio.us  Digg  Technorati  reddit
    Furl CiteUlike Connotea

    Share





Research - Abstract

  Cite this article:

Abiodun Christopher Jemilohun, Jesse Abiodun Otegbayo, Samuel Olawale Ola, Olayiwola Abideen Oluwasola, Adegboyega Akere. Prevalence of helicobacter pylori among Nigerian patients with dyspepsia in Ibadan.
The Pan African Medical Journal. 2010;6:18

Key words: Dyspepsia, Helicobacter pylori, Histology, Rapid urease test, Nigeria

Permanent link: http://www.panafrican-med-journal.com/content/article/6/18/full

Received: 28/07/2010 - Accepted: 19/09/2010 - Published: 20/09/2010

© Abiodun Christopher Jemilohun et al.   The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Prevalence of helicobacter pylori among Nigerian patients with dyspepsia in Ibadan

 

Abiodun Christopher Jemilohun1,&, Jesse Abiodun Otegbayo2, Samuel Olawale Ola, Olayiwola Abideen Oluwasola3, Adegboyega Akere2

           

1Department of Medicine, Ladoke Akintola University of Technology Teaching Hospital, Oshogbo, Nigeria, 2Department of Medicine, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria, 3Department of Morbid Anatomy and Histopathology, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria

 

 

&Corresponding author

Abiodun Christopher Jemilohun, Department of Medicine, Ladoke Akintola University of Technology Teaching Hospital, Oshogbo, phone: +2348038674623, P.M.B. 5000, Oshogbo, Osun State, Nigeria

 

 

Introduction

 

Determination of the true prevalence of Helicobacter pylori (H. pylori) is difficult in a hyper-endemic area like Nigeria with use of serological tests because of their low discriminatory power between previous and current infections. The use of biopsy based methods will go a long way to mitigate this problem. We investigated the prevalence of H. pylori in dyspeptic patients and its relationship with gastroduodenal pathologies using gastric biopsy histology and rapid urease test.

 

 

Methods

 

Eighty-six consecutive adult patients with dyspepsia underwent upper gastrointestinal endoscopy using forward-viewing endoscopes. Antral biopsy specimens were collected for histology and rapid urease test. Diagnosis of H. pylori infection was made if both or either of the tests was positive.

 

 

Results

 

Of the 86 subjects, there were 39 (45.3%) males and 47(54.7%) females. The age range was 23 to 85 years with a mean of 49.1913.75 years. Diagnosis of H. pylori was made in 55(64%) patients. Gastritis was the commonest endoscopic finding (60.5%), serious gastroduodenal pathology (gastric ulcer, duodenal ulcer and gastric cancer) were documented in only 12 (14%) patients. Thirty three (63.5%) of the 55 patients with gastritis had H. pylori infection while 7(58.3%) of the 12 patients with serious gastroduodenal lesions had the infection. Thirteen (72.2%) of the 18 patients that had normal endoscopic findings were H. pylori positive.

 

 

Conclusion

 

The prevalence of H. pylori among dyspeptics using biopsy based methods is high in the South-Western part of Nigeria. It is therefore important to test and treat H. pylori among Nigerians with dyspepsia.