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Shivaraj Gowda, Prakash Desai, Vinayak Hull, Avinash Math, Sonal Vernekar, Shruthi Kulkarni. A review on liver function test. The Pan African Medical Journal. 2009;3:17 Key words: Laboratory liver test, bilirubin, alanine amino transferase, aspartate amino transferase, ratio of aminotransferases, alkaline phosphatase, gamma glutamyl transferase, 5´nucleotidase, ceruloplasmin, alpha-fetoprotein Permanent link: http://www.panafrican-med-journal.com/content/article/3/17/full Received: 04/09/2009 - Accepted: 18/11/2009 - Published: 25/11/2009 © Shivaraj Gowda et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
A review on laboratory liver function tests
Shivaraj Gowda1&, Prakash Desai1, Vinayak Hull1, Avinash Math1, Sonal Vernekar1, Shruthi Kulkarni1,
1Department of Biochemistry, J. N. Medical College, Belgaum 590010. Karnataka. India
&Corresponding author
Shivaraj Gowda, Department of Biochemistry, J.N.Medical College, Belgaum 590010. Karnataka. India.
Abstract
Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic pathway which are very sensitive for the abnormality occurred may be considered as biochemical marker of liver dysfunction. Some of the biochemical markers such as serum bilirubin, alanine amino transferase, aspartate amino transferase, ratio of aminotransferases, alkaline phosphatase, gamma glutamyl transferase, 5´ nucleotidase, ceruloplasmin, alpha-fetoprotein are considered in this article. An isolated or conjugated alteration of biochemical markers of liver damage in patients can challenge the clinicians during the diagnosis of disease related to liver directly or with some other organs. The term “liver chemistry tests” is a frequently used but poorly defined phrase that encompasses the numerous serum chemistries that can be assayed to assess hepatic function and/or injury.
