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Caroline Edijana Omoti, Alexander Ikenna Nwannadi, Jude Chike Obieche, Adesuwa Noma Olu-Eddo. The epidemiological features of lymphoid malignancies in Benin City, Nigeria: a 15 years study. The Pan African Medical Journal. 2012;11:10 Key words: Epidemiology, lymphoma, leukemia, myeloma, morphology, Nigeria Permanent link: http://www.panafrican-med-journal.com/content/article/11/10/full Received: 19/11/2010 - Accepted: 23/11/2011 - Published: 20/01/2012 © Caroline Edijana Omoti et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
The Epidemiological features of lymphoid malignancies in Benin City, Nigeria: A 15 years study
Caroline Edijana Omoti1, Alexander Ikenna Nwannadi1, Jude Chike Obieche1, Adesuwa Noma Olu-Eddo1
1University of Benin Teaching Hospital P.M.B. 1111, Benin City, Nigeria
&Corresponding author
Caroline Edijana Omoti Consultant Haematologist, Department of Haematology and Blood Transfusion, University of Benin Teaching Hospital, P.M.B. 1111, Benin City, Nigeria
Lymphoid malignancies compose a wide spectrum of different morphologic and clinical syndromes known to vary widely throughout the world. The purpose of this study is to determine the prevalence and time trends of lymphoid malignancies.
A 15 (May 1st 1996-April 30th 2010) years study of all patients who had lymph node biopsy at the Department of Haematology and Pathology, University of Benin Teaching Hospital, Benin City, Nigeria.
The 391 patients had a male preponderance (M:F; 1.6:1). An increase in the lymphoid malignant cases was noted from 95 cases in the first 5-year interval (1996-2000) to 179 cases in the last 5-year interval (2006-2010) giving an average increase of 84.0%. Non-Hodgkins lymphoma (61.1%) and chronic lymphocytic leukaemia (18.2%) were the most frequent followed by Hodgkin’s lymphoma and myeloma with equal proportions of 9.0% each. A positive correlation with a significant linear trends was obtained (r=0.1949, p<0.0001). Geographic areas at risk were found mainly in patients residing in Delta State (67.0%) which is a major oil producing state and Edo State (30.4%) where the hospital is located, both in the Niger Delta Region of Nigeria.
Future research into environmental agents and genetic makeup/HLA typing of patients can be carried out.
