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Imananagha Kobina Keme-Ebi, Asindi Asindi Asindi. Locked in Syndrome in a Nigerian male with Multiple Sclerosis. A case report and literature review. The Pan African Medical Journal. 2008;1:4 Key words: Locked-in Syndrome, Nigeria Permanent link: http://www.panafrican-med-journal.com/content/article/1/4/full Received: 31/09/2008 - Accepted: 27/10/2008 - Published: 30/10/2008 © Imananagha Kobina Keme-Ebi et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Locked–in Syndrome in a Nigerian male with Multiple Sclerosis: a case report and literature review
Imananagha Kobina Keme-Ebi1,2, & , Asindi Asindi Asindi2
1Department of Medicine, Neurologic Unit, Niger Delta University Teaching Hospital, Okolobiri, Nigeria; 2Department of Paediatrics, Neurologic Unit, University of Calabar Teaching Hospital, Calabar, Nigeria;
&Corresponding author
Imananagha Kobina Keme-Ebi, MD, Ph.D, Department of Medicine, Niger Delta University Teaching Hospital, Okolobiri ( PO BOX 1109, Yenagoa), Bayelsa State, Nigeria.
Background
Locked-in syndrome is an extremely difficult neurologic condition to recognize, especially by the non-specialists. A case of locked-in syndrome in a 41–year old Niger Deltan Nigerian with relapsing remitting form of multiple sclerosis (MS) is presented, including a detailed literature review.
Patient and Case Report
The patient was in a state of spastic quadriplegia, motionless and aphasic (mute), with the preservation of consciousness and the ability to open and blink the eyes and move them vertically. Two episodes of the disease, varying in duration, have been described. The diagnosis of MS was made from the history and the typical clinical presentation: history of relapsing and remitting signs and clinical evidence of multi-focal involvement of the central nervous system.
Conclusion
Patient died at the age of 45 years, from pulmonary complications. This article may enhance easy recognition and management of the syndrome by all clinicians.
